Is the Mattress Protector Hypo-Allergenic? March 30, 2022 19:47 Updated Yes, the mattress protector is made of cotton terry, which is designed to be both easy care and hypo-allergenic Related articles Is the Mattress Protector a Full Encasement? Can I use a Box Spring on Top of the High Rise Platform Foundation? How Do I Set Up My Mattress? Do Your Sheets Work on a Mattress Over 11" Thick? How long does it take for my mattress to break-in?