Is the Mattress Protector Hypo-Allergenic? March 30, 2022 19:47 Updated Yes, the mattress protector is made of cotton terry, which is designed to be both easy care and hypo-allergenic Related articles Will the Mattress Protector Reduce Breathability of the Mattress? Is the Mattress Protector a Full Encasement? Do Your Sheets Work on a Mattress Over 11" Thick? What If My Mattress Feels Too Firm? Can I use a Box Spring on Top of the High Rise Platform Foundation?